Men's Phthalate Levels Linked to Pregnancy Trouble

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Credit: Anthony Berenyi | Shutterstock
(Image credit: Anthony Berenyi | Shutterstock)

Women whose male partners have high levels of hormone-mimicking chemicals known as phthalates take longer to become pregnant, according to new research.

Phthalates are used in food packaging, plastics and personal products such as fragrances and shampoos. Similar to bisphenol A (BPA), phthalates are thought to interfere with hormone systems, but whether current levels of people's exposure to these chemicals are dangerous to their health is debated.

Neither the men's nor the women's levels of BPA seemed to affect how long it took to get pregnant. However, it took couples 20 percent longer to get pregnant if the man had high levels of three common phthalates, according to the study. [12 Hormone-Disrupting Chemicals & Their Health Effects]

The findings suggest that "exposure to certain phthalates can reduce the chance of conception for otherwise healthy couples," said study researcher Germaine Buck Louis, director of population health research at the National Institutes of Health (NIH).

"The delays in pregnancy we saw were comparable to those seen for cigarette smoking, or with obesity," Buck Louis said in a statement.

The researchers examined only the time it took to achieve pregnancy, and not how the compounds might affect fertility. Further work is needed to determine if the compounds affect reproductive health and hormone levels, the researchers said.

Previous studies have linked exposure to BPA and phthalates with pregnancy problems in women, and findings from animal studies suggest these chemicals can hinder the maturation of egg cells, disrupt hormones and alter the development of reproductive organs, the researchers said.

Studies have also suggested a link between men's hormone levels and exposure to BPA, and some have found high concentrations of BPA and phthalates among couples seeking treatment for infertility, the researchers said.

The new findings show that it's important to study both partners when assessing the effects of chemicals on pregnancy outcomes, Buck Louis said. "Clearly, in studies of this kind, males matter."

The study was published online Feb. 18 in the journal Fertility and Sterility.

Email Bahar Gholipour. Follow us @LiveScience, Facebook & Google+. Original article on Live Science.

Bahar Gholipour
Bahar Gholipour
Staff Writer
Bahar Gholipour is a staff reporter for Live Science covering neuroscience, odd medical cases and all things health. She holds a Master of Science degree in neuroscience from the École Normale Supérieure (ENS) in Paris, and has done graduate-level work in science journalism at the State University of New York at Stony Brook. She has worked as a research assistant at the Laboratoire de Neurosciences Cognitives at ENS.