NASA Fed Apollo 11 Moon Rocks to Cockroaches (And Then Things Got Even Weirder)

Lab technicians study mice that were injected with lunar material collected during Apollo 11 in a photo taken in August 1969.

(Image credit: NASA)

It's too weird to make up: NASA fed some of its precious Apollo 11 lunar samples to cockroaches. And dumped it in fishbowls. And injected mice with it. No, really.

NASA still has most of the moon rocks the Apollo 11 crew brought home, but a small fraction of the astronauts' bounty was used up in a little-known but vitally important set of experiments that ensured lunar samples were safe to keep here on Earth.

Scientists were pretty sure that there weren't any potentially dangerous germs living on the moon, but they couldn't be absolutely sure. And while the retrieval of moon rocks was an incredible gift to science, it could have been quite a curse on Earth if those rocks had turned out to be a risk to terrestrial life. So as part of the agency's preparations for the mission, NASA had to put together a program of tests.

"We had to prove that we weren't going to contaminate not only human beings, but we weren't going to contaminate fish and birds and animals and plants and you name it," Charles Berry, who was in charge of medical operations during Apollo, said in a 1999 oral history. "Any of the Earth's biosphere, we had to prove we weren't going to affect it. So we had to develop an amazing program that was carried off really for three flights' worth. A lot of trouble."

The astronauts themselves were shuffled into quarantine after their return to Earth, where they remained isolated from all but 20 humans for three weeks, from the moment Neil Armstrong and Buzz Aldrin left the moon. A collection of mice also shot to fame while the astronauts were in quarantine: They were injected with lunar material and were monitored just as closely as the crew, who also joined in the watch.

"They always wanted to know how the rodents were doing," Judith Hayes, chief of NASA's Biomedical Research and Environmental Sciences Division, who used to work in the building that once housed the quarantine facility and who has talked with scientists who accompanied the astronauts during that time, told Space.com. "If the rodents did well, then they would likely be released on time, if the rodents weren't well, they would likely be examined much more carefully and longer."

First, NASA chose the species it would use. In addition to the mice, the agency and its partners also selected other representative species: Japanese quail to represent birds, a couple of nondescript fish, brown shrimp and oysters for shellfish, German cockroaches and houseflies for creepy-crawlies, and more. (Sadly, while we found images of the mice, birds and plants, the moon rock-eating roaches eluded us.)

Then, the agency tapped into its precious cache of 49 lbs. (22 kilograms) of newly delivered lunar material. Scientists ground everything to dust, half of which they baked to sterilize and half of which they left as it was. The prescription varied a little with animal type: mice and quail got the lunar sample as an injection, insects had the sample mixed into their food and aquatic animals had the moon dust added to the water they lived in.

NASA watched the menagerie for a month in case anything seemed to suffer from the lunar exposure. The German cockroaches that were fed moon dust — true to the insects' reputation — thrived despite the exotic diet. And all the animals did well, with one glaring exception: Whether in lunar water or not, many of the oysters died, which the scientists chalked up to having tested animals during their mating season.

In addition to testing animals, NASA also worked with the U.S. Department of Agriculture (USDA) to test plants for any adverse reactions to lunar material, just in case. (As a USDA employee newsletter published in August 1969 recounted, "What will a little moon dust do to your tomato plants? Probably nothing.") These experiments included growing seeds in lunar soil and tested not just tomatoes, but also tobacco, cabbage, onion and fern. Some of these plants actually grew better in the regolith than in the sand scientists used as a comparison.

Meghan is a senior writer at Space.com and has more than five years' experience as a science journalist based in New York City. She joined Space.com in July 2018, with previous writing published in outlets including Newsweek and Audubon. Meghan earned an MA in science journalism from New York University and a BA in classics from Georgetown University, and in her free time she enjoys reading and visiting museums. Follow her on Twitter at @meghanbartels.