Why Your Next Flu Shot Will Be Different

doctor holding needle
(Image credit: Dreamstime)

Next season's flu shot will contain two new flu strains that weren't present in last season's shot, according to the Centers for Disease Control and Prevention.

Health officials are making the change in the hope that next season's flu shot — which will be released in the autumn — will be a better match to the strains that are actually circulating, and will do a better job of preventing flu cases.

Last season's flu shot was not very effective at preventing the flu: People who got the shot were just 19 percent less likely to visit the doctor for flu than people who did not get the shot, according to a new CDC report. That level of protection is quite a bit lower than for previous seasons — for example, during the 2012 to 2013 flu season, getting the flu shot reduced people's risk of needing a doctor's visit for flu by 56 percent.

The poor protection offered by last season's flu shot was likely the result of a mismatch between the flu strains included in that vaccine and the strains that were circulating in the public.

Most of the flu viruses circulating last fall and winter belonged to a strain known as H3N2. But about 80 percent of the H3N2 viruses in circulation were different from the H3N2 strain included in the 2014 to 2015 flu shot, the CDC report stated. Such mismatch can happen because the virus's genetic material changes slightly, or "drifts," over time.

Therefore, health officials are switching out one of the three strains included in next season's trivalent flu shot, and two of the four strains included in the quadrivalent flu shot.

The trivalent flu vaccine protects against two influenza A strains, H1N1 and H3N2, and one influenza B strain. For the 2015 to 2016 flu season, the H1N1 strain and the influenza B strain will remain the same as last season's, but health officials are putting in a different H3N2 strain, called A/Switzerland/9715293/2013 (H3N2)-like virus, the CDC said.

The quadrivalent flu vaccine protects against the same strains as the trivalent vaccine, as well as an extra influenza B virus. For the 2015 to 2016 flu season, the quadrivalent flu shot will contain the same strains as the trivalent flu shot, as well as a new influenza B strain called B/Phuket/3073/2013-like (B/Yamagata lineage) virus. [6 Flu Vaccine Myths]

This past flu season was particularly severe for older adults, with this age group experiencing the highest rate of flu hospitalizations in a decade, the CDC said. Between October 2014 and April 2015, there were about 322 hospitalizations per 100,000 people among U.S. adults ages 65 and over, the new report found. Previously, the highest rate of hospitalizations for this age group was 183 flu hospitalizations per 100,000 people, which occurred during the 2012 to 2013 flu season.

The 2014 to 2015 flu season was also a particularly long flu season; the percentage of doctor's visits that were related to flu was elevated for 20 consecutive weeks, the report said. During the past 13 flu seasons, the percentage of doctor's visits for flu was elevated for an average of 13 weeks.

The number of flu cases typically drops in the summer, but doctors should still be on the lookout for flu, and consider it as a possible cause of summer respiratory illness, the CDC said.

Follow Rachael Rettner @RachaelRettner. Follow Live Science @livescience, Facebook & Google+. Original article on Live Science.

Rachael Rettner

Rachael is a Live Science contributor, and was a former channel editor and senior writer for Live Science between 2010 and 2022. She has a master's degree in journalism from New York University's Science, Health and Environmental Reporting Program. She also holds a B.S. in molecular biology and an M.S. in biology from the University of California, San Diego. Her work has appeared in Scienceline, The Washington Post and Scientific American.