Ants can detect the scent of cancer in urine

An ant drinking water pooling on a leaf.
Since they don't have noses, ants use their antennae to sniff out cancer. (Image credit: Rob Ault via Getty)

Ants can be trained to detect cancer in urine, a new study finds.

Although ant sniffing is a long way from being used as a diagnostic tool in humans, the results are encouraging, the researchers said.

Because ants lack noses, they use olfactory receptors on their antennae to help them find food or sniff out potential mates. For the study, published Jan. 25 in the journal Proceedings of the Royal Society B: Biological Sciences (opens in new tab), scientists trained nearly three dozen silky ants (Formica fusca) to use these acute olfactory receptors for a different task: finding tumors.

In a lab, scientists grafted slices of breast cancer tumors from human samples onto mice and taught the 35 insects to "associate urine from the tumor-bearing rodents with sugar," according to The Washington Post (opens in new tab). Once placed in a petri dish, the ants spent 20% more time next to urine samples containing cancerous tumors versus healthy urine, according to the study.

"They just want to eat sugar," Baptiste Piqueret (opens in new tab), the study's lead author and an ethologist at Sorbonne Paris North University in France, told The Washington Post.

Related: Some cancer cells grow stronger after chemo. Research hints at how to kill them.

Because tumor cells contain volatile organic compounds (VOCs) that researchers can use as cancer biomarkers, animals such as dogs — and now ants — can be quickly trained to detect these anomalies through their sense of smell. However, researchers think that ants "may have the edge over dogs and other animals that are [more] time-consuming to train," according to The Washington Post. 

This is important because the earlier cancer is detected, the sooner treatment can begin. The researchers are hopeful that cancer-sniffing ants have the potential "to act as efficient and inexpensive cancer bio-detectors," they wrote in their study. 

"The results are very promising," Piqueret said. However, he cautioned that "it's important to know that we are far from using them as a daily way to detect cancer."

Jennifer Nalewicki
Live Science contributor

Jennifer Nalewicki is a Salt Lake City-based journalist whose work has been featured in The New York Times, Smithsonian Magazine, Scientific American, Popular Mechanics and more. She covers several science topics from planet Earth to paleontology and archaeology to health and culture. Prior to freelancing, Jennifer was a reporter at Interior Design Magazine, and before that she held an Editor role at Time Inc. Jennifer has a bachelor's degree in Journalism from The University of Texas at Austin.

  • Big Crow
    seems more likely they're going after sugar in the urine, detecting cancer is of no use to them.
    Reply
  • bolide2
    Big Crow said:
    seems more likely they're going after sugar in the urine, detecting cancer is of no use to them.
    They were trained to associate cancer urine with sugar. The experimental proof was that after training they spent more time with the cancer urine than with healthy urine. If the experimenters were competent, they controlled the samples for sugar content.
    Reply