The lightest known metal can also lighten your mood. Lithium, atomic number 3, is an element of many uses. It's used in the manufacture of aircraft and in certain batteries. It's also used in mental health: Lithium carbonate is a common treatment of bipolar disorder, helping to stabilize wild mood swings caused by the illness.
Lithium has a flashy discovery story — literally. A Brazilian naturalist and statesman, Jozé Bonifácio de Andralda e Silva, discovered the mineral petalite (LiAISi4O10) on the Swedish isle Utö in the 1790s, according to the Royal Society of Chemistry (RSC). The mineral is white to gray, but when thrown into fire, it flares bright crimson.
In 1817, Swedish chemist Johan August Arfwedson discovered that petalite contained a previously unknown element. He wasn't able to isolate the metal entirely, but he did isolate one of its salts. The name, lithium, comes from "lithos," the Greek word for "stone."
It took until 1855 for someone to isolate lithium: British chemist Augustus Matthiessen and German chemist Robert Bunsen ran a current through lithium chloride to separate the element.
According to the Jefferson National Linear Accelerator Laboratory, the properties of lithium are:
- Atomic number (number of protons in the nucleus): 3
- Atomic symbol (on the Periodic Table of Elements): Li
- Atomic weight (average mass of the atom): 6.941
- Density: 0.534 grams per cubic centimeter
- Phase at room temperature: Solid
- Melting point: 356.9 degrees Fahrenheit (180.5 degrees Celsius)
- Boiling point: 2448 degrees Fahrenheit (1342 degrees Celsius)
- Number of isotopes (atoms of the same element with a different number of neutrons): 10; 2 stable
- Most common isotopes: Li-7 (92.41 percent natural abundance), Li-6 (7.59 percent natural abundance)
The brain on lithium
Lithium is a special metal in many ways. It's light and soft — so soft that it can be cut with a kitchen knife and so low in density that it floats on water. It's also solid at a wide range of temperatures, with one of the lowest melting points of all metals and a high boiling point.
Like its fellow alkali metal, sodium, lithium reacts with water in showy form. The combo of Li and H2O forms lithium hydroxide and hydrogen, which typically bursts into red flame.
Lithium makes up a mere 0.0007 percent of the Earth's crust, according to the Jefferson Lab, and it's only found locked up in minerals and salts. Those salts have the power to change the brain: Lithium salts were the first drugs approved by the Food and Drug Administration to treat mania and depression, according to the National Institute of Mental Health.
Today, lithium carbonate is the compound most often sold as a pharmaceutical. No one knows exactly how lithium works to stabilize mood. Studies show multiple effects on the nervous system. In 2008, for example, researchers reported in the journal Cell that lithium interrupts the activity of a receptor for the neurotransmitter dopamine. It also appears to plump up brain volume, according to a 2011 study in the journal Biological Psychiatry (though this research is hotly contested).
In a study with worms, biologists at MIT found that lithium inhibits a key protein in the worms' brain, making neurons linked to an avoidance behavior go dormant. Essentially, the worms stopped avoiding harmful bacteria without that protein. The findings, which would need to be replicated in humans, suggest the element silences certain neurons in the brain and may have a calming effect, the researchers reported in 2016 in the journal Current Biology.
Lithium in space
Lithium, as well as the first and second lightest chemical elements (hydrogen and helium, respectively), are the only elements created at the birth of the universe, according to NASA. However, according to the Big Bang Theory, the universe should hold three times as much lithium as can be accounted for in the oldest stars, an issue called the missing lithium problem. This "missing lithium" discovery was first made in the 1980s, said Pasquale Serpico, a cosmologist at the National Center for Scientific Research (CNRS) and the University of Savoy Mont Blanc in France. It created a "tension," Serpico said, between what the Big Bang data and the observations of stars were telling researchers about lithium's abundance.
Astrophysicists continue to conduct research to find this "missing" lithium or to explain why it's missing. In fact, researchers recently found a giant star holding 3,000 times more lithium than normal "giants," they reported in August 2018 in the journal Nature Astronomy. They came up with two possible explanations: the giant star swallowed its planet, absorbing the onboard lithium; the lithium also may have formed inside the star, reaching its surface before the heat of the deep layers vaporized it, according to a statement on the finding.
More about lithium
- Lithium-ion batteries are the key to lightweight, rechargeable power for laptops, phones and other digital devices. According to the U.S. Geological Survey, Argentina and Chile increased their lithium production 15 percent each in 2014 alone to meet the growing demand. Worldwide, production jumped 6 percent that year.
- Lithium and another battery component, cobalt, could become scarce as demand increases, Stefano Passerini and Daniel Buchholz, both at the Helmholtz Institute Ulm in Germany, said in a statement describing their analysis of the future availability of those elements published in 2018 in the journal Nature Reviews Materials. In addition, both are concentrated in less politically stable countries, the study revealed. As such, the researchers urged the development of new battery technologies based on other, non-toxic elements.
- The United States has one lithium mine, in Nevada, according to the USGS. Chile and Australia produce the most lithium in the world.
- Naturally occurring lithium in drinking water correlates with lower levels of suicide, according to a 2009 study that highlights lithium's role in the brain. But psychiatrists are careful about prescribing lithium in high doses, particularly because it can pass through the placenta and have unknown effects on the developing fetus.
- On a lighter note, the element is part of celebratory fireworks shows: A mix of lithium and strontium salts, along with some other chemicals, creates the show's brilliant red color.
- Los Alamos National Laboratory: Lithium
- Jefferson Lab: The Element Lithium
- U.S. National Library of Medicine: Lithium (medication)
This article was updated on Oct. 23, 2018 by Live Science Managing Editor, Jeanna Bryner.
Live Science newsletter
Stay up to date on the latest science news by signing up for our Essentials newsletter.
Stephanie Pappas is a contributing writer for Live Science, covering topics ranging from geoscience to archaeology to the human brain and behavior. She was previously a senior writer for Live Science but is now a freelancer based in Denver, Colorado, and regularly contributes to Scientific American and The Monitor, the monthly magazine of the American Psychological Association. Stephanie received a bachelor's degree in psychology from the University of South Carolina and a graduate certificate in science communication from the University of California, Santa Cruz.