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Newly Discovered Brain Region Helps Make Humans Unique

Human brain illustrated with interconnected small nerves - 3d render
Human brain integrates signals simultaneously coming from different senses. (Image credit: <a href="">Johan Swanepoel</a> | <a href="">Shutterstock</a>)

Scientists have identified a part of the brain that seems to be unique to humans.

The brain region, called the lateral frontal pole prefrontal cortex, was described today (Jan. 28) in the journal Neuron, and is linked to higher thinking processes.

"We tend to think that being able to plan into the future, be flexible in our approach and learn from others are things that are particularly impressive about humans," Matthew Rushworth, an experimental psychologist at Oxford University, said in a statement. "We've identified an area of the brain that appears to be uniquely human, and is likely to have something to do with these cognitive powers,"

The new brain region is located within a larger region called the ventrolateral frontal cortex, which in past studies has been tied to higher thinking. For instance, this part of the brain houses Broca's region, which plays a critical role in language. Differences in the ventrolateral frontal cortex have also been tied to psychiatric disorders such as compulsive behavior disorders and attention deficit hyperactivity disorder (ADHD).

Rushworth and his colleagues put 25 people who were each 20 years old into a magnetic resonance imaging (MRI) scanner. The research team next mapped connections among different regions of the ventrolateral frontal cortex, then divided the brain region into 12 areas that seemed to be constant across all participants.

The researchers then compared the mapped region to the same brain region in 25 rhesus macaque monkeys, who had also undergone MRI scans.

The monkey brains were strikingly similar to human brains in 11 out of 12 of the areas identified. But one area, called the lateral frontal pole prefrontal cortex, was found only in the human volunteers.

In addition, the whole ventrolateral frontal cortex was more connected to auditory parts of the brain in humans, perhaps to facilitate better language processing.

"We have established an area in human frontal cortex which does not seem to have an equivalent in the monkey at all," said study co-author Franz-Xaver Neubert of Oxford University, in a statement. "This area has been identified with strategic planning and decision making, as well as 'multi-tasking.'"

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Tia Ghose

Tia has interned at Science News,, and the Milwaukee Journal Sentinel and has written for the Center for Investigative Reporting, Scientific American, and ScienceNow. She has a master's degree in bioengineering from the University of Washington, a graduate certificate in science writing from the University of California Santa Cruz, and an undergraduate degree in mechanical engineering from the University of Texas at Austin. At the Milwaukee Journal Sentinel, Tia was part of the team that produced the Empty Cradles series on preterm births in the city, which won a 2012 Casey Medal for Meritorious Journalism, as well as the 2012 print award from the National Academy of Sciences, National Academy of Engineering and Institute of Medicine.