Osteoarthritis: Causes, Symptoms & Treatment

Discovery Could Lead to Reversal of Arthritis

Osteoarthritis, also known as degenerative joint disease, occurs when cartilage between the joints wears down over time, which can cause pain, loss of motion, swelling and joint stiffness. The most commonly affected joints are the knees, hips, neck, tips of the fingers, thumbs and lower back.

Without cartilage between the bones at the joint, the bones rub together painfully, and the joint may even warp from its normal shape. Small bone spurs can grow on the edges of the joint, which can cause discomfort, reports The National Institute of Arthritis and Musculoskeletal and Skin Diseases. Pieces of bone or cartilage can also break away and float inside the joint, leading to additional pain and problems.

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Rachael Rettner
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Rachael is a Live Science contributor, and was a former channel editor and senior writer for Live Science between 2010 and 2022. She has a master's degree in journalism from New York University's Science, Health and Environmental Reporting Program. She also holds a B.S. in molecular biology and an M.S. in biology from the University of California, San Diego. Her work has appeared in Scienceline, The Washington Post and Scientific American.