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Heartburn Drug Found to Contain Traces of Cancer-Causing Chemical

Containers of the drug Zantac.
(Image credit: Shutterstock)

U.S. health officials have found low levels of a potentially cancer-causing chemical in a popular heartburn drug.

On Friday (Sept. 13), the U.S. Food and Drug Administration (FDA) announced that samples of ranitidine — known by the brand name Zantac — were found to contain a contaminant called N-nitrosodimethylamine (NDMA). That's the same chemical that was found in heart and blood pressure medications last year, sparking numerous recalls of those affected drugs.

NDMA is classified as a "probable human carcinogen" because it has been found to cause cancer in animal studies. The chemical forms as a byproduct of certain industrial processes, and it was formerly used in the production of rocket fuel, according to the U.S. Environmental Protection Agency. It is found in low levels in drinking water and some foods, including certain meat and dairy products.

"Although NDMA may cause harm in large amounts, the levels the FDA is finding in ranitidine from preliminary tests barely exceed amounts you might expect to find in common foods," Dr. Janet Woodcock, director of the FDA's Center for Drug Evaluation and Research, said in a statement.

Originally published on Live Science. 

Rachael Rettner
Contributor

Rachael is a Live Science contributor, and was a former channel editor and senior writer for Live Science between 2010 and 2022. She has a master's degree in journalism from New York University's Science, Health and Environmental Reporting Program. She also holds a B.S. in molecular biology and an M.S. in biology from the University of California, San Diego. Her work has appeared in Scienceline, The Washington Post and Scientific American.