Product of Olive Oil Could Help Deliver Drugs

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The nanogels could be used for tissue engineering, artificial membranes, and drug delivery. (Image credit: Jonathan Dordick, Rensselaer Polytechnic Institute)

Sugar and olive oil may not mix well in a jar. But in the lab, scientists have used them to create a very tiny capsule that can be loaded with medicine or food.

The new "organogel" was made by adding a simple enzyme to activate a sugar, which changed olive oil and other liquid solvents into organic gels.

"We are using the building blocks provided by nature to create new nanomaterials that are completely reversible and environmentally benign," said study leader Jonathan Dordick of Rensselaer Polytechnic Institute.

When the sugar is activated, a compound that self-assembles into three-dimensional fibers is created. The fibers measure almost 50 nanometers in diameter. A nanometer is one billionth of a meter; a human hair is roughly 100,000 nanometers wide.

When the fibers intertwine, the large amounts of solvent pack together and trap about 10,000 molecules.

"The development of new materials that are molecularly defined and chemically functional at the nanoscale is of critical importance to biological applications such as drug delivery," Dordick said. "We are finding the natural world has provided tools to create these materials without the need to generate new compounds that may be harmful to the body or environment."

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Sara Goudarzi
Sara Goudarzi
Sara Goudarzi is a Brooklyn writer and poet and covers all that piques her curiosity, from cosmology to climate change to the intersection of art and science. Sara holds an M.A. from New York University, Arthur L. Carter Journalism Institute, and an M.S. from Rutgers University. She teaches writing at NYU and is at work on a first novel in which literature is garnished with science.