Stephen Hawking, Famed Physicist Who Defied ALS Odds, Dies at 76
Stephen Hawking in 2006.
Credit: The World in HDR/Shutterstock

Stephen Hawking, one of the brightest minds of modern physics, has died at the age of 76 at his home in Cambridge, England, The Guardian reported today (March 14). He was perhaps the best-known physicist in the world, despite having to communicate via a computerized voice that recorded the minute motion of his cheek muscle.

"We are deeply saddened that our beloved father passed away today," Lucy, Robert and Tim Hawking, the children of the physicist, said in a statement announcing his death. "He was a great scientist and an extraordinary man whose work and legacy will live on for many years."

Hawking was a brilliant student of physics at the University of Cambridge when he was diagnosed with the degenerative nerve disease amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, at the age of 21. ALS affects the neurons that help us move our muscles, so Hawking used a wheelchair for decades and communicated via a computerized "voice." He nevertheless continued working and soon developed a series of groundbreaking theories that would remake the world of physics. In 1966, the cosmologist published his doctoral thesis, which argued that the entire universe began as a singularity.  

He then went on to reshape our understanding of black holes. Until Hawking's work, scientists believed absolutely nothing could escape a black hole, meaning that a black hole would grow ever larger. But Hawking posited that quantum mechanics essentially allowed black holes to emit particles — a phenomenon now known as Hawking radiation.

Hawking was also a deeply witty popularizer of some of the most esoteric concepts in physics and cosmology, with books such as "A Brief History of Time" (Bantam Books, 1988). In recent years, he weighed in on everything from the future of humanity, to the risks of artificial intelligence, to the chances of Earth turning into Venus, all while continuing to publish important theoretical work in physics.

Editor's note: This article was updated at 10:14 am to include information about how ALS affects the body.

Originally published on Live Science.